Is challenging first time around (bank rules / government laws in Africa and in our country around scams / money laundering, terrorism etc) – but after the first transfer it is extremely easy – no different to transfers within your country. 

No costs are taken out except (bank / currency costs) so all your money you give gets there.

They are not tied to a charity in your country so tax-deductibility in your country is up to you. These are African organisations dealing direct with children on their own, which makes their efforts even more meritorious and worthy of support.